Flamazine Antibacterial Cream 50g Tube SM

FLAMAZINE cream U.S.A.N.: Silver Sulfadiazine
Chemical nameSilver 2-(4-aminobenzenesulfonamido)-pyrimidine Molecular Formula: C ₁₀ H ₉ N ₄ O ₂ S Ag Molecular Weight: 357.14
Description:
Silver sulfadiazine is a light-stable white powder, very slightly soluble in water and most organic solvents, but readily soluble in nitric acid and concentrated ammonia solutions.

Composition
FLAMAZINE cream is a white cream containing 1% w/w silver sulfadiazine in a water soluble vehicle. The pH of the cream is between 3.5-6.0.

The mechanism of silver sulfadiazine's antibacterial action has not been fully elucidated. After exposure to the drug, structural changes in the bacterial cell membrane occur, including distortion and enlargement of the cell and a weakening of the cell wall membrane. This is accompanied by reduced viability in sensitive strains due to interference with macromolecular synthesis. The sulfadiazine moiety also provides a bacteriostatic action against sensitive organisms. In adults, up to 10% of the sulfadiazine may be absorbed and 60-85 % of the absorbed amount is excreted in the urine. In children with 13 % body surface area burns, the urinary sulfadiazine concentration was 31.8 mg/L.
Inactive ingredientsPolysorbate 60 - vegetable grade Polysorbate 80 - vegetable grade Glyceryl Stearate Cetyl Alcohol Propylene Glycol Liquid Paraffin Distilled Water

Sterility
FLAMAZINE E cream is a sterile compound and contains no preservatives.