Vaccine Hepatitis-A Havrix 1440 SM

HAVRIX, hepatitis A vaccine, is a sterile suspension containing formaldehyde - inactivated hepatitis A virus (HM 175 hepatitis A virus strain) adsorbed onto aluminium hydroxide. The virus is propagated in MRC5 human diploid cells. Before viral extraction, the cells are extensively washed to remove culture medium constituents. A virus suspension is then obtained by lysis of the cells followed by purification using ultrafiltration techniques and gel chromatography. The virus is then inactivated with formalin. Residual formaldehyde in the vaccine should be not more than 0.01%. Suspension for injection. One dose (1.0 ml) of Havrix 1440 Adult contains: Hepatitis A virus (inactivated)1,2 1440 ELISA Units 1Produced on human diploid (MRC-5) cells 2Adsorbed on aluminium hydroxide, hydrated Total: 0.50 milligrams A